Connacht's only defeat to a Welsh visitor in the last five such matches in Galway was to Ospreys in May.
Cardiff Blues achieved an eleven try demolition of Zebre in round 1 but then slipped up to Leinster in Dublin the following week.
The Blues have lost their last seven away fixtures since overcoming Wasps 45-42 at the Ricoh Arena in the Anglo-Welsh Cup in February - an encounter in which they were losing by 25 points with less than half an hour left.
Connacht have won just one of their last eleven fixtures against The Blues: 26-22 at BT Sport Cardiff Arms Park in 2013, whilst Blues solitary away win at an Irish province since January 2013 came when they visited Galway at the end of the 2013/14 PRO12 season.
At Sportsground, 5pm.
Referee: Neil Hennessy (WRU, 22nd competition game)
Assistant Referees: Keiran Barry, Paul Haycock (both IRFU)
Citing Commissioner: Gordon Black (IRFU)
Connacht Rugby
36 - 31
HT: 19 - 17
Cardiff Blues
3rd October 2015
17:00
The Sportsground
3274
GUINNESS PRO12