The half backs are confirmed with Chris Smylie as scrum half and Sam Christie as fly half.
Marco Barbini, Robert Barbieri and Dean Budd are named in the back row.
The second row has a new partnership with Duncan Naude and Tom Palmer.
Loose head prop Matteo Zanusso, Rupert Harden tight head prop and the permit player Roberto Santamaria as hooker
Benetton Rugby:
15 Jayden Hayward
14 Ludovico Nitoglia
13 Tommaso Iannone
12 Andrea Pratichetti
11 Simone Ragusi
10 Sam Christie
9 Chris Smylie
8 Robert Barbieri
7 Dean Budd
6 Marco Barbini
5 Tom Palmer
4 Duncan Naudè
3 Rupert Harden
2 Roberto Santamaria
1 Matteo Zanusso
Replacements
16 Luca Bigi
17 Alberto De Marchi
18 Simone Ferrari
19 Jeff Montauriol
20 Andrea De Marchi
21 Abraham Steyn
22 Alberto Lucchese
23 James Ambrosini
Coach: Umberto Casellato
At Kingspan Stadium, 6:05pm. Live on BBC NI
Referee: Lloyd Linton (SRU, 9th competition game)
Assistant Referees: Sean Gallagher, Brian MacNeice (both IRFU)
Citing Commissioner: Eddie Wigglesworth (IRFU)
TMO: Kevin Beggs (IRFU)
