It promises to be an emotional occasion for Ball who was born just 15 miles away from Twickenham in Ascot.
But the second row - who has made eight RaboDirect PRO12 starts for Scarlets this season - isn't about to let his heart rule his head.
"I'm just glad I had the opportunity the week before and I don't look at this one any differently," Ball told the South Wales Evening Post.
"Against France I didn't really know what I was running out into. I didn't expect the lights to be off, the fireworks and everything else. It all just flashed by really quickly. It was case of controlling the emotions through the anthems, but it's a dream, isn't it, to play international rugby. It was great.
"I'm just going to go out there and do what I do best. I just want to get stuck in and play my natural game."
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