This is Ulster's best start to a new campaign since they set the Championship record of winning their opening 11 contests in season 2012/13.
Ospreys had recorded maximum league points after three rounds but were brought back down to earth with a 19-31 loss to Leinster on Friday.
Ospreys only victory in their last five encounters with Irish provinces was 32-11 over Connacht in Galway in round 2.
Things could not be more even in previous encounters between the two sides with each attaining 13 victories, however of late Ulster's only loss to Ospreys in their last six meetings was 20-31 at Liberty Stadium in December 2014.
Ospreys have won just once at Kingspan Stadium since 2010: 16-12 in February 2013.
Overall Guinness PRO12 head to head record:
Played 26, Ulster won 13, Ospreys won 13.
At Kingspan Stadium, 6.30pm. Live on Sky Sports
Referee: Ben Whitehouse (WRU, 29th competition game)
Assistant Referees: Sean Brickell (WRU), Paul Haycock (IRFU)
Citing Commissioner: Eddie Wigglesworth (IRFU)
TMO: Gareth Simmonds (WRU)
Guinness PRO12
Suite 208, Alexandra House,
The Sweepstakes
Ballsbridge, Dublin 4, Ireland














