The Leinstermen are unbeaten in their last 18 home games in the PRO12, including a run of 16 successive victories.
The Leinstermen have only ever lost twice to a fellow Irish province at the RDS Arena: to Munster in September 2008 and to Ulster in March 2013.
Connacht have won their last four matches with the two most recent taking them to the top of pool two in the European Champions Cup.
Connacht's only defeat in their last five encounters with an Irish opponent was 10-18 in Ulster in April.
Connacht have won their last two matches against Leinster including last season's Guinness PRO12 final and have never tallied three successive wins against their neighbours since the two first locked horns in 1931, however Connacht have not been victorious in Dublin since a 26-23 win at Donnybrook in the PRO12 in
September 2002.
Overall Guinness PRO12 head to head record:
Played 28, Leinster won 20, Connacht won 8.
At RDS Arena, 5.15pm. Live on Sky Sports
Referee: John Lacey (IRFU, 57th competition game)
Assistant Referees: Andy Brace, Jonathan Peak (both IRFU)
Citing Commissioner: Tim Lowry (IRFU)
TMO: Olly Hodges (IRFU)
Guinness PRO12
Suite 208, Alexandra House,
The Sweepstakes
Ballsbridge, Dublin 4, Ireland