Glasgow have won their last four matches against Edinburgh since the capital side's 39-6 victory at Murrayfield on 26 December 2008.
Edinburgh Rugby have won just one of their last four games in all competitions, but have been victorious in their last four matches at Murrayfield.Glasgow Warriors ended a three game losing run in all competitions with their 30-18 victory in the first leg of the 1872 Cup on Monday.
Referee: Neil Paterson (SRU, 29th League game).
Assistant Referees: David Changleng, Graeme Marshall (both SRU).
TMO: Ian Ramage (SRU).
Live on BBC Alba.