In the backs, Gilberto Pavan will play at outside centre alongside Gabriel Pizarro.
Naas Olivier returns at 10 to pair up with Tito Tebaldi, who is back at scrum-half after playing fly-half in Dublin.
There are two changes in the back row, where only Nick Williams preserves his spot in the starting line-up. Nicola Cattina and Frans Viljoen are the flankers. For the sixth game in a row George Biagi and Joshua Furno make up the second row. In the front row Matias Aguero returns in place of Alberto De Marchi, with Fabio Staibano at tight head and captain Roberto Santamaria as hooker.
AIRONI
15 Ruggero Trevisan; 14 Sinoti Sinoti, 13 Gilberto Pavan, 12 Gabriel Pizarro, 11 Giovanbattista Venditti; 10 Naas Olivier, 9 Tito Tebaldi; 8 Nick Williams, 7 Nicola Cattina, 6 Frans Viljoen; 5 George Biagi, 4 Joshua Furno; 3 Fabio Staibano, 2 Roberto Santamaria (cap), 1 Matias Aguero.
Replacements: 16 Davide Giazzon, 17 Alberto De Marchi, 18 Luca Redolfini, 19 Josh Sole, 20 Simone Favaro, 21 Tyson Keats, 22 Roberto Quartaroli, 23 Riccardo Pavan.
Coach: Rowland Phillips.
Guinness PRO12
Suite 208, Alexandra House,
The Sweepstakes
Ballsbridge, Dublin 4, Ireland