Damien Hoyland's first-half try-double set the tone as Edinburgh won their first game under acting head coach Duncan Hodge in style.
Hoyland - who scored twice the last time he faced Treviso - was joined on the scoresheet by Hamish Watson and Magnus Bradbury in a half that saw Edinburgh wrap up the try-bonus point.
And though Marco Fuser's try cut into the deficit after the break, this was to be Edinburgh's night as Tom Brown - with help from an inspired Jason Tovey - added two more tries for the hosts.
Blair Kinghorn, on his first start of the season, rounded things off with another try at the death.
Hodge had promised the BT Murrayfield a big performance and it looked as if he would prove true to his word when Hoyland touched down with four minutes gone.
The Scotland wing was first to react to a loose ball from a ruck and stormed across the whitewash from some 70 yards out, with Welsh fly-half Tovey converting.
The hosts doubled up moments later, this time Chris Dean doing all the hard work with a superb break before Watson broke through the tackles to touch down.
Tovey made it two conversions from two before the game settled down for a spell - and crucially for Treviso, Tommaso Allan slotted a penalty to get them on the board.
But Hoyland piled the pain on the Italians on the half-hour with another smart finish and Tovey was on target for the third time with the extras.
Hoyland was involved once more soon after, combining with Dean and Mike Allen before back-rower Bradbury was set free to race home from 60 metres out.
Tovey took his personal tally to eight with the conversion and suddenly Edinburgh were 26-3 to the good, which is stayed until half-time.
Treviso showed admirable spirit upon the restart and responded when Marco Fuser rumbled over four minutes into the half, Allan on target with the extras.
It was only to be momentary respite for Treviso - who have not won away from home since December 2014 - as a sumptuous Tovey miss pass opened up the space for Brown to dive over.
Edinburgh made a slew of replacements on the hour mark including a first Edinburgh appearance for young prop Murray McCallum.
The hosts' sixth of the night also came through Brown and Tovey was the creator again, placing his cross-field kick where only his wing could reach it.
Tovey's kick then put Edinburgh 40 up before Kinghorn finished a flowing move to round off a morale-boosting night for the home side.
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