The Province travel to Wales to take on a Scarlets side who beat Gloucester last weekend and who have a squad packed full of internationals.
Ludik, who joined Ulster in the summer, starts the game at full back. Michael Allen is selected on the right wing with Jared Payne and Stuart Olding picked in the centre.
Craig Gilroy starts on the left wing with Ian Humphreys and Paul Marshall maintaining their partnership in the half-backs.
Up front, Callum Black starts at loosehead, Rob Herring, who won his first cap for Ireland in the summer, is selected at hooker and new summer addition, Herbst, is named at tighthead.
Ireland's Dan Tuohy an d Springbok Franco van der Merwe are paired in the second row, while there is an all Ireland international back row with Robbie Diack, Chris Henry starting either side of captain Roger Wilson.
John Andrew is selected among the substitutes and is set for his first competitive appearance for Ulster.
Ireland international Luke Marshall and IRUPA Players' Player of the Season for 2013/14, Andrew Trimble, are also selected on the bench.
The game is live on Sky Sports 1 and BBC Radio Ulster.
Ulster XV and replacements to face Scarlets, Guinness PRO12, Parc Y Scarlets, Saturday 6th September (kick off 14:40): (15-9) L Ludik, M Allen, J Payne, S Olding, C Gilroy, I Humphreys, P Marshall; (1-9); C Black, R Herring, W Herbst, D Tuohy, F van der Merwe, R Diack, C Henry, R Wilson (C); Replacements: J Andrew, A Warwick, D Fitzpatrick, L Stevenson, N Williams, M Heaney, L Marshall, A Trimble.
Guinness PRO12
Suite 208, Alexandra House,
The Sweepstakes
Ballsbridge, Dublin 4, Ireland