Leicester made a fine start to their European campaign with a bonus-point win over Stade Français.
That made it four wins in five games in all competitions this season, and they look to be finding some form.
A number of new faces arrived over the summer, with openside Brendon O'Connor stealing the show against Stade with some fantastic work at the breakdown, including setting up Leicester's first try with a steal.
For their part, Treviso went down to GUINNESS PRO12 rivals Munster in round one, and are still chasing their first win of the season.
Saturday November 21, kick-off 2:00pm UK/Ire
Benetton Treviso: Luke McLean, Ludovico Nitoglia, Enrico Bacchin, Samuel Christie, Tommaso Iannone, James Ambrosini, Edoardo Gori (c), Matteo Zanusso, Ornel Gega, Rupert Harden, Filo Paulo, Jean-François Montauriol, Marco Barbini, Francesco Minto, Abraham Jurgens Steyn
Replacements: Davide Giazzon, Matteo Muccignat, Filippo Filippetto, Dean Budd, Marco Lazzaroni, Alberto de Marchi, Christopher Smylie, Andrea Pratichetti
Leicester Tigers: Telusa Veainu, Peter Betham, Matthew Tait (c), Matt Smith, Vereniki Goneva, Thomas Bell, Sam Harrison, Marcos Ayerza, Tom Youngs, Fraser Balmain, Dom Barrow, Michael Fitzgerald, Tom Croft, Brendon O'Connor, Jordan Crane
Replacements: Greg Bateman, Matias Aguero, Dan Cole, Ed Slater, Lachlan McCaffrey, Ben Youngs, Seremaia Bai, George Catchpole
Bath v Leinster
Bath have made an up-and-down start to their Premiership season with two wins from four games but picked up five points in their last game against London Irish.
Their Champions Cup opener against Toulon was postponed because of the terror attacks in Paris so they come into this game very fresh.
Francois Louw will captain the side after returning from the World Cup with South Africa, while George Ford will pull the strings at fly-half.
The teams met in the quarter-final stage last year with Leinster narrow winners in Dublin. Having lost their opener at home to Wasps, Leinster need a win to get their campaign back on track.
Saturday November 21, kick-off 3:15pm UK/Ire
Bath Rugby: Anthony Watson, Semesa Rokoduguni, Ollie Devoto, Kyle Eastmond, Matt Banahan, George Ford, Chris Cook, Nick Auterac, Rob Webber, Henry Thomas, Dom Day, David Attwood, Matt Garvey, Francois Louw (c), Leroy Houston
Replacements: Ross Batty, Nathan Catt, Max Lahiff, Stuart Hooper, Alafoti Fa'osiliva, Niko Matawalu, Rhys Priestland, Tom Homer
Leinster Rugby: Isa Nacewa (c), Fergus McFadden, Ben Te'o, Luke Fitzgerald, Dave Kearney, Johnny Sexton, Isaac Boss, Cian Healy, Sean Cronin, Mike Ross, Devin Toner, Hayden Triggs, Rhys Ruddock, Jordi Murphy, Jamie Heaslip
Replacements: James Tracy, Jack McGrath, Martin Moore, Dominic Ryan, Josh Van Der Flier, Luke McGrath, Ian Madigan, Zane Kirchner
Glasgow Warriors v Northampton Saints
Glasgow take on a familiar foe on Saturday when they host Northampton, having faced off at the same stage of the competition three seasons ago.
That year a late Peter Horne try gave Glasgow a thrilling win in the Scotstoun clash, and since both teams have gone onto win their domestic titles.
While the Warriors are the reigning GUINNESS PRO12 champions, Northampton's maiden league title came in 2014.
They've struggled early in the league this season with just one win from four games, but turned over the Scarlets at home last time out.
A powerful set of forwards lay the foundations for them, even in the absence of skipper Dylan Hartley, and fly-half Stephen Myler returns to the starting line-up this weekend.
Glasgow's opener away at Racing 92 was called off last week so they come into this one fresh.
Saturday November 21, kick-off 5:15pm UK/Ire
Glasgow Warriors: Stuart Hogg, Tommy Seymour, Mark Bennett, Peter Horne, Sean Lamont, Finn Russell, Mike Blair, Ryan Grant, Pat MacArthur, Sila Puafisi, Leone Nakarawa, Jonny Gray (c), Robert Harley, Simone Favaro, Josh Strauss
Replacements: Shalva Mamukashvili, Gordon Reid, Zander Fagerson, Tim Swinson, Ryan Wilson, Grayson Hart, Richie Vernon, Taqele Naiyaravoro
Northampton Saints: Ben Foden, Ah See Tuala, George Pisi, Luther Burrell, George North, Steve Myler, Lee Dickson (c), Alex Waller, Mikey Haywood, Kieran Brookes, Michael Paterson, Christian Day, Jamie Gibson, Tom Wood, Sam Dickinson
Replacements: Matti Williams, Ethan Waller, Paul Hill, Jonathan Fisher, Teimana Harrison, Kahn Fotuali'i, JJ Hanrahan, Jamie Elliott
Scarlets v Racing 92
While they are still waiting for their biggest summer signing, Dan Carter, Racing 92 have put together a formidable squad and look a real contender to reach the knock-out stages.
Quarter-finalists last year, they have plenty of experience up front, with France hooker Dimitri Szarzewski leading the side.
In the backs, the likes of Joe Rokocoko and Casey Laulala are extremely dangerous with ball in hand while scrum-half Maxime Machenaud is having a great season.
Racing have lost just twice all season, but were well-beaten at Castres in their last Top 14 game.
The two teams last met the season before last, playing out a thrilling 26-26 draw at Parc Y Scarlets before the Welsh side won in Paris later in the season. The Scarlets need a win having picked up a losing bonus point at Saints last week.
Saturday November 21, kick-off 5:30pm UK/Ire
Scarlets: Aled Thomas, Michael Tagicakibau, Gareth Owen, Hadleigh Parkes, DTH van der Merwe, Dan Jones, Gareth Davies, Phil John, Ken Owens (c), Peter Edwards, Jake Ball, Maselino Paulino, Aaron Shingler, James Davies, John Barclay
Replacements: Emyr Phillips, Dylan Evans, Samson Lee, Tom Price, Lewis Rawlins, Aled Davies, Mike Collins, Steff Evans
Racing 92: Johannes Goosen, Joe Rokocoko, Casey Laulala, Henry Chavancy, Marc Andreu, Remi Tales, Maxime Machenaud, Julien Brugnaut, Dimitri Szarzewski (c), Cedate Gomes Sa, Luke Charteris, Francois van der Merwe, Bernard Le Roux, Wenceslas Lauret, Chris Masoe
Replacements: Camille Chat, Eddy Ben Arous, Ben Tameifuna, Thibault Dubarry, Yannick Nyanga, Mike Phillips, Juan Imhoff, Brice Dulin
Zebre v Worcester Warriors
Worcester have made a successful return to the top flight in England so far, with two wins from four in the Premiership, followed by last weekend's Challenge Cup win over La Rochelle.
Dean Ryan's men have already opened up a sizable gap to the bottom of the Premiership table as they look to secure safety in the top flight.
This weekend they will be captained by scrum-half Jean-Baptiste Bruzulier, who has returned to the club after a short spell at Clermont earlier in the season as a medical joker.
Ryan Lamb scored 14 of Worcester's 19 points last week, and will link up with Bruzulier in the half-backs.
Zebre were beaten at Gloucester last time out but won their last home game, a GUINNESS PRO12 success against Cardiff Blues.
Saturday November 21, kick-off 3:00pm UK/Ire
Zebre Rugby: Guglielmo Palazzani, Dion Berryman, Giulio Bisegni, Gonzalo Garcia, Leonardo Sarto, Carlo Canna, Marcello Violi, Andrea Lovotti, Andrea Manici, Dario Chistolini, Quintin Geldenhuys, George Biagi (c), Jacopo Sarto, Johan Meyer, Dries van Schalkwyk
Replacements: Oliviero Fabiani, Andrea de Marchi, Pietro Ceccarelli, Valerio Bernabo, Paul Derbyshire, Luke Burgess, Tommaso Boni, Edoardo Padovani
Worcester Warriors: Ben Howard, Perry Humphreys, Max Stelling, Alex Grove, Dean Hammond, Ryan Lamb, JB Bruzulier (c), Ryan Bower, Jaba Bregvadze, Gareth Milasinovich, Dan Sanderson, Darren O'Shea, Carl Kirwan, Sam Betty, Marco Mama
Replacements: Ben Sowrey, Derrick Appiah, Joe Rees, Darren Barry, Matt Cox, Charlie Mulchrone, Ryan Mills, Tom Biggs
Castres v Newport Gwent Dragons
Castres' game with Pau last weekend was called off, so they make their first appearance in the Challenge Cup for six seasons.
New coach Christophe Urios is clearly taking this game against Newport Gwent Dragons seriously, and has named a strong team.
In the pack Piula Faaselele is a dangerous ball-carrier with a combination of strength and surprising pace. He will be joined by former Glasgow number eight Johnnie Beattie in the back row.
In the backs Remi Grosso earned his first French cap during the World Cup and is one of the in-form wingers in France.
The Dragons, meanwhile, come into the game off the back of a good win over Sale but have not yet won on the road this season.
Saturday November 21, kick-off 5:00pm UK/Ire
Castres Olympique: Geoffrey Palis, Romain Martial, Thomas Combezou, Romain Cabannes (c), Remi Grosso, Daniel Kirkpatrick, Julien Seron, Saimone Taumoepeau, Marc-Antoine Rallier, Yohan Montes, Christophe Samson, Victor Moreaux, Piula Faasalele, Alexandre Bias, Johnnie Beattie
Replacements: Mathieu Bonello, Mihaita Lazar, Lucas Martinez, Alex Tulou, Theo Hannoyer, Julien Dumora, Remi Lamerat, Antoine Dupont
Newport Gwent Dragons: Carl Meyer, Ashton Hewitt, Adam Hughes, Adam Warren, Nick Scott, Dorian Jones, Sarel Pretorius, Phil Price, Elliot Dee, Shaun Knight, Matthew Screech, Rynard Landman (c), Nick Crosswell, Ollie Griffiths, Ed Jackson
Replacements: Rhys Buckley, Boris Stankovich, Lloyd Fairbrother, Cory Hill, Nic Cudd, Charlie Davies, Jason Tovey, Ross Wardle
Connacht v Brive
Brive have been one of the surprise packages in the Top 14 season and are currently fifth in the table, level on points with triple European champions Toulon.
They opened their European campaign with a win over Newcastle, battling to a 13-9 success, but face a tough challenge in Connacht.
Winger Benito Masilevu will be a real danger man, having made a huge impact on arrival from Fiji's sevens team last season.
Connacht will look to build on last week's win in Siberia against Enisei. They finally returned home from that epic adventure on Tuesday, but as GUINNESS PRO12 leaders, they will go into the game full of confidence.
Saturday November 21, kick-off 5:00pm UK/Ire
Connacht Rugby: Tiernan O'Halloran (c), Rory Parata, Robbie Henshaw, Bundee Aki, Danie Poolman, Jack Carty, Kieran Marmion, Ronan Loughney, Jason Harris Wright, Nathan White, Ben Marshall, Andrew Browne, Eoghan Masterson, Nepia Fox Matamua, Eoin McKeon
Replacements: David Heffernan, Conan O'Donnell, Finlay Bealham, Danny Qualter, George Naoupu, Ian Porter, Craig Ronaldson, Niyi Adeolokun
Brive: Romain Sola, Elia Radikedike, Benjamin Petre, Christopher Tuatara, Benito Masilevu, Matthieu Ugalde, Jean-Baptiste Pejoine (c), Damien Lavergne, Thomas Acquier, Kevin Buys, Johan Snyman, Wilhem Steenkamp, Hugues Briatte, Poutasi Luafutu, William Whetton
Replacements: Guillaume Ribes, Goderzi Shvelidze, Giorgi Jgenti, Victor Lebas, Said Hireche, Teddy Iribaren, Alfi Mafi, Sevanaia Galala
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