Rob Kearney is again selected at full back with brother Dave continuing on the left wing and club captain Isa Nacewa coming in on the right.
There is a positional switch at centre with Ben Te'o moving to outside and Luke Fitzgerald coming into the starting XV at inside centre.
In the half backs Luke McGrath has recovered from the foot infection that kept him out of last week's starting XV and he will be joined by Johnny Sexton who has himself shaken off a knee injury that forced him to leave the pitch early last week.
In the pack Jack McGrath and Richardt Strauss start again and are joined at tight head prop by Tadhg Furlong. Devin Toner - for his 175th Leinster cap - and Mike McCarthy start again in the second row.
In the back row last week's captain Rhys Ruddock is joined by fellow Irish internationals Sean O'Brien and Jamie Heaslip.
On the bench Noel Reid is back involved in a match day squad for the first time since recovering from an ankle injury and is in line to win his 50th cap for Leinster.
LEINSTER:
15. Rob Kearney
14. Isa Nacewa CAPTAIN
13. Ben Te'o
12. Luke Fitzgerald
11. Dave Kearney
10. Johnny Sexton
9. Luke McGrath
1. Jack McGrath
2. Richardt Strauss
3. Tadhg Furlong
4. Devin Toner
5. Mike McCarthy
6. Rhys Ruddock
7. Sean O'Brien
8. Jamie Heaslip
16. Sean Cronin
17. Peter Dooley
18. Marty Moore
19. Tom Denton
20. Dominic Ryan
21. Eoin Reddan
22. Ian Madigan
23. Noel Reid
Referee: David Wilkinson (IRFU, 37th competition game)
Assistant Referees: Ben Whitehouse, Simon Rees (both WRU)
Citing Commissioner: Aurwel Morgan (WRU)
TMO: Jon Mason (WRU)