Edinburgh Rugby travel to Newport looking to better their recent run of three successive losing bonus points on the road, at a ground at which they have not tasted success since 2006.
Head coach Alan Solomons, said: "There is no question that this is an important game.
"We're disappointed that we didn't come away with the result at the weekend. We had a number of opportunities to put points on the board and we didn't, and that cost us.
"Yes, it is positive that we are getting closer on the road but it's important that we get a result and that we understand the significance of this game.
"We need to make sure that, when we create chances, we finish them.
"We need to deliver a top-flight performance and, in any big game, that means you take your chances when they come and you give away very little."
Solomons has made two personnel changes to the side that lost to Treviso in Italy (20-16).
Jack Cuthbert moves to his favoured full-back role at the expense of Carl Bezuidenhout - who takes a place on the bench - with Sam Hidalgo-Clyne starting on the wing.
The 20 year-old has made nine appearances for the club at scrum-half in his debut season but an impressive replacement appearance on Saturday has earned him the call.
In the pack Mike Coman returns to captain the team from the blind-side of the back-row, so Cornell Du Preez starts on the open-side and Roddy Grant moves to the bench, where he is joined by recent arrival Simon Berghan, who replaces the injured Ewan McQuillin (neck strain).
Solomons said: "Sam [Hidalgo-Clyne] is scrum-half and that's where I'd like to see him longer-term but he has the ability to play on the wing without a problem given his experience in the back three as a Scotland age-grade internationalist.
"His is an outstanding young talent and, even though he had just a cameo, he looked dangerous. He has great feet, pace, is brave and strong. It's great to have him involved in the team.
"I think Mike [Coman] has really good leadership qualities. He adds great value to the team in that respect.
"That said, this is as much a rotation of the loose forwards, as Roddy Grant has had an outstanding season for us."
Edinburgh Rugby team to play Dragons at Rodney Parade tomorrow (Thursday 3 April, kick-off 6.30pm) - live on BBC ALBA/S4C
15 Jack Cuthbert
14 Sam Hidalgo-Clyne
13 Matt Scott
12 Andries Strauss
11 Tom Brown
10 Harry Leonard
9 Grayson Hart
1 Alasdair Dickinson
2 Ross Ford
3 Willem Nel
4 Grant Gilchrist
5 Izak van der Westhuizen
6 Mike Coman CAPTAIN
7 Cornell Du Preez
8 David Denton
Substitutes
16 James Hilterbrand
17 Wicus Blaauw
18 Simon Berghan
19 Ollie Atkins
20 Roddy Grant
21 Sean Kennedy
22 Carl Bezuidenhout
23 Sam Beard
Guinness PRO12 Edinburgh News
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