The Warriors edged the first leg of the 1872 Cup at Christmas time after Stuart Hogg had the final word in Edinburgh, before the weather forced the reschedule of their second clash.
And the RaboDirect PRO12 record between the two rivals makes grim reading for Alan Solomons' men, losing each of their last four games since a 23-23 draw at Murrayfield in 2011.
Gilchrist, however, intends on using the disappointment of last time out to good effect on Saturday - and turn a good performance into points.
"I thought that for 60 minutes we were the better team," Gilchrist told The Herald. "Around that time we had been playing some good stuff and had been building towards that game and for 60 minutes we did what we set out to do and dominated physically.
"But with one turnover, they spun the ball wide and scored and that hurt us.
"I was bitterly disappointed after the game, it was tough to take.
"Like everything, we are professional athletes and want to win games of rugby with this club and have been on the losing end too many times, especially against Glasgow.
"It is only us who can fix it and we aim to do that this weekend."
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