A change at centre sees Matt Scott return at outside centre with Andries Strauss at inside, following injury to Phil Burleigh last time out. On-loan Jason Tovey remains at stand-off with Sean Kennedy moving from the bench to start in the number nine jersey.
The pack, meanwhile is unchanged, the Scotland front row of Alasdair Dickinson, Ross Ford and WP Nel bookended by the back row of Jamie Ritchie on the blindside, John Hardie at openside and Cornell Du Preez at no 8.
The lock combination of Anton Bresler and Ben Toolis is retained, with the former set to make his 50th appearance in the black and red.
The 6ft 6in Namibian-born second row arrived at the club at the start of 2014/15 making 26 appearances - 23 starts - last season and 23 to date, just one off the bench, this term.
Bresler said: "It's a huge honour to be named in this side to earn my fiftieth cap for Edinburgh.
"Since the day I arrived, the club have really welcomed me and I love the family environment we've created. I'm really enjoying my time here.
"We have a really challenging game tomorrow. We know how tough the Irish provinces are at home - we were reminded of that last time out against Leinster - but we'll be going all out to ensure we stay in the top six going into our last game.
"With the final match of the season at home, it would be fantastic to have a great home crowd at BT Murrayfield cheering us on to reach the upper level of European competition next season."
Edinburgh currently sit in sixth place in the Guinness PRO12 and must retain that position to achieve the aim of moving into the European Champions Cup mix for 2016/17.
Last season the club beat Munster in the opening away fixture, at Thomond Park, however were edged at BT Murrayfield, 14-16, the last time the sides met.
Players not considered due to injury: Michael Allen (shoulder), Phil Burleigh (leg), Mike Coman (calf), Jack Cuthbert (knee), Grant Gilchrist (arm), Nasi Manu (neck), Fraser McKenzie (neck), Jade Te Rure (knee).
Edinburgh Rugby v Munster
Friday 29 April, Irish Independent Park, kick-off 7.35pm
15. Blair Kinghorn
14. Damien Hoyland
13. Matt Scott
12. Andries Strauss
11. Tom Brown
10. Jason Tovey
9. Sean Kennedy
1. Alasdair Dickinson
2. Ross Ford (captain)
3. WP Nel
4. Anton Bresler
5. Ben Toolis
6. Jamie Ritchie
7. John Hardie
8. Cornell Du Preez
Substitutes
16. Stuart McInally
17. Rory Sutherland
18. John Andress
19. Alex Toolis
20. Magnus Bradbury
21. Sam Hidalgo-Clyne
22. Chris Dean
23. Dougie Fife