The first of two changes to the pack sees hooker Niall Scannell join Dave Kilcoyne and John Ryan in the front row. Mark Chisholm and captain Billy Holland continue in the second row, while in the back row, Tommy O'Donnell returns at 7 with Dave O'Callaghan and Jack O'Donoghue switching to 6 and 8 respectively.
Simon Zebo starts on the left wing in an otherwise unchanged backline. Duncan Williams and Ian Keatley form the half-back partnership and Rory Scannell makes his tenth consecutive start at inside centre in partnering Francis Saili in the midfield.
Winger Darren Sweetnam and fullback Andrew Conway again complete the starting XV.
If called upon from the bench, recent long-term injury returnee Johnny Holland will make his first appearance of the season.
In other news, this week saw Mario Sagario called up to the Uruguayan international squad for the Americas Rugby Championship. The Munster tighthead will start against the USA in Montevideo tomorrow.
Munster: Andrew Conway; Darren Sweetnam, Francis Saili, Rory Scannell, Simon Zebo; Ian Keatley, Duncan Williams; Dave Kilcoyne, Niall Scannell, John Ryan; Mark Chisholm, Billy Holland - capt.; Dave O'Callaghan, Tommy O'Donnell, Jack O'Donoghue.
Replacements: Mike Sherry, James Cronin, Stephen Archer, Dave Foley, Robin Copeland, Cathal Sheridan, Johnny Holland, David Johnston.