Simon Keogh starts on the left wing with Rob Kearney moving to full-back for the visit of Connacht, with Felipe Contepomi continuing his centre partnership with Luke Fitzgerald.
Meanwhile in the pack, Shane Jennings has recovered from injury to take his place at openside flanker, while Stephen Keogh and Cameron Jowitt also come into the starting line-up.
The final list of replacements will be confirmed closer to kick off.
As well as the usual 'Family Day' with face-painting, bouncy castles and the Canterbury Roadshow, Friday will have a 'Kids Takeover' theme whereby a number of lucky young supporters will read out the team announcements, help deliver the match ball and interview the players after the match for Leinster TV.
Friday night will see the province pass the 100,000 attendance mark for home matches as over 15,000 tickets have now been sold for the visit of Connacht.
All supporters are advised to use Public Transport and to arrive early on the day.
Tickets can be purchased on www.leinsterrugby.ie and discounted tickets may still be available from the Leinster Rugby Store and Spar Donnybrook. Tickets will be on sale from the Ticketmaster box office on Simmonscourt Road and Anglesea Road from 5pm on Friday.
LEINSTER:
15: Rob Kearney
14: Gordon D'Arcy
13: Luke Fitzgerald
12: Felipe Contepomi
11: Simon Keogh
10: Isa Nacewa
9: Chris Whitaker CAPTAIN
1: Cian Healy
2: John Fogarty
3: Stan Wright
4: Trevor Hogan
5: Cameron Jowitt
6: Rocky Elsom
7: Shane Jennings
8: Stephen Keogh
REPLACEMENTS FROM: Brian Blaney, Ronan McCormack, Malcolm O'Kelly, Devin Toner, Sean O'Brien, Jamie Heaslip, Chris Keane, Jonathan Sexton, Shane Horgan, Brian O'Driscoll
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