The New Zealand-born forward, who represented Ireland 'A', has been a valued member of the Edinburgh squad and made 38 appearances in the Black and Red during two seasons.
Now the ex-Leinster man is preparing to return to Dublin after gaining valuable experience while working with Stew-Mel's forwards over the past eight months.
Gissing said: "I would like to wish everyone at Edinburgh well and I've got lots of good memories of my time at the club; including beating both Leinster and Leicester in the Heineken Cup.
"Scoring a try at Toulouse last season was also a good experience. Coaching Stewart's Melville has been tremendous and it was very good to get the whole experience under my belt while working with such a good bunch of guys.
"Achieving something with Stew-Mel was really memorable. Now I've got some other coaching options in the pipeline back in Ireland."
Former Edinburgh captain Meyer, who led the side against Ospreys last season, has also decided to retire from full-time rugby and plans to return to his native Auckland.
Meyer said: "I'm going back to New Zealand and I'm hoping to get involved in the professional development side of sport.
"I would either like to get involved in New Zealand's Academy of Sport or work as a professional development officer for the Super 14 or at Provincial level.
"There are limited opportunities with those, so I may have to bide my time. The programme is about career planning, financial advice, education and off field stuff.
"I've always been a big advocate of that type of stuff because I've played semi-professionally back home. My time here has been one of only two times when I've done rugby full-time."
As Edinburgh's unofficial vice club captain - supporting Simon Cross in his role - Meyer says he has enjoyed his time in Scotland.
He said: "The highlights would be getting to play at such a phenomenal stadium such as Murrayfield, working with people like Andy (Robinson) and Rob (Moffat), being in a team full of international players and being made captain for the home game against Ospreys last season.
"I've actually really enjoyed playing for Selkirk this season and winning the Gala 7s and also the social side of Edinburgh Rugby. My sense of humour seems to have been accepted and that has been enjoyable.
"I hope I have made a difference to the team culture at Edinburgh. When I joined it was quite disjointed with quite a few new players joining at the same time.
"I had this idea about gelling everything together. Simon (Cross) has done a great job as club captain and I don't think he gets a lot of credit for the work he has done.
"I was just interested in helping him out; I don't want any accolades or credit for it. I just want to make sure that when I go somewhere new, I leave it in a better shape then when I found it - I think we've done that."
Edinburgh Rugby Club would like to thank both players for their contributions, both on and off the pitch, over the past two seasons and wish them well as they embark on the next chapters of their careers.
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