Both Niva Ta'auso and Frank Murphy have overcome their respective hamstring and calf injuries to start for Connacht in the backline, while up front Ronan Loughney comes in at tighthead prop and Johnny O'Connor returns to the starting line up at openside.
Gavin Duffy moves from outside centre to fullback, making way for Ta'auso and Andrew Browne moves to his more familiar position in the second row, with Ray Ofisa starting for Connacht for the first time at number eight.
Connacht team:
G Duffy; F Carr, N Ta'auso, K Matthews, L Bibo; I Keatley, F Murphy; B Wilkinson, S Cronin, R Loughney; A Browne, A Farley; J Muldoon (C), J O'Connor, R Ofisa.
Replacements:
A Flavin, B McGovern, M Swift, C Rigney, C O'Loughlin, A Dunne, T Nathan.
Not considered due to injury:
Kieran Campbell (hip), Tim Donnelly (knee), John Hearty (hip), Michael McCarthy (foot), Robbie Morris (foot).
Guinness PRO12
Suite 208, Alexandra House,
The Sweepstakes
Ballsbridge, Dublin 4, Ireland