Andy Dunne starts for the first time and Conor O'Loughlin has been included to partner him in the half back positions. Darren Yapp also comes into the side at second centre for the injured Daniel Riordan.
Both David Gannon and John Fogarty have passed fitness tests this week and are both included among the replacements which also includes Matt Mostyn for the first time since last November, after overcoming ankle and calf injuries.
This is Connacht's final Magners League match at home before the new year and Michael Bradley is eager to put the record straight after last weeks game against Ulster.
"We are frustrated by our own lack of success in the Ulster match but that was our first loss at home this season and we want to put the record straight," said Bradley.
"We're aware that Glasgow are playing good rugby but the fact we are at home is a big factor in our favour."
Connacht team:
G Duffy; A Wynne, D Yapp, M Deane, O Treviranus; A Dunne, C O'Loughlin; B Wilkinson, A Flavin, R Morris; M Swift, A Farley (C); M McCarthy, J O'Connor, J Muldoon.
Replacements:
J Fogarty, R Loughney, D Gannon, R Ofisa, C McPhillips, T Donnelly, M Mostyn.
Injured:
Keith Matthews (rib), John Hearty (hip), John Lyne (calf), Daniel Riordan (quad).
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