With Ross Ford, Gavin Kerr and Kelly Brown making their return to the pack, Chris Cusiter pulls on the captain's armband for the first time in over four months having last captained the side against Ulster at Ravehill in November.
Elsewhere, Bryan Rennie returns to the back-line alongside Ben MacDougall in the centre.
Looking forward to tomorrow's game, Reivers head coach Steve Bates said: Tomorrow's game will be another huge challenge against a side full of international players.
"I hope that we will see a fast and exciting game that allows the players from both sides to show the national selectors what they can do in the run up to the World Cup."
Border Reivers team to play Edinburgh Rugby in the Magners League at Netherdale on Friday 23 March (kick-off 7:30pm)
15 Stuart Moffat
14 Dougie Flockhart
13 Ben MacDougall
12 Bryan Rennie
11 Garry Law
10 Gregor Townsend
9 Chris Cusiter CAPTAIN
1 Gavin Kerr
2 Ross Ford
3 Bruce Douglas
4 John Dalziel
5 Opeta Palepoi
6 Scott Newlands
7 Andy Miller
8 Kelly Brown
Substitutes
16 Steve Scott
17 Ed Kalman
18 Richie Vernon
19 Scott Forrest
20 Rob Chrystie
21 Steve Jones
22 Brendon Daniel
Guinness PRO12
Suite 208, Alexandra House,
The Sweepstakes
Ballsbridge, Dublin 4, Ireland