The South African coach, Franco Smith, lines up most of the players seen last week in Newport, but can rely also on some other players came back from the National team.
The only permit player to be lined up will be last week's try scorer flanker from Petrarca Padova, Filippo Giusti, while Manoa Vosawai, who is replacing Robert Barbieri, Tommaso Iannone and Michele Rizzo are starting as first string.
The prop and the flanker are the only new entries in the pack, while among the backs Giulio Toniolatti is playing full-back, Doppies La Grange is playing inside centre with Andrea Pratichetti as outside centre.
As for the half-backs, Fabio Semenzato is playing together with Italian-Australian James Ambrosini, at his second appearance as first string fly-half since the Heineken Cup match against Leicester Tigers of last December.
Referee of the match will be Welsh Leighton Hodges.
Starting line-up:
15 Giulio Toniolatti
14 Ludovico Nitoglia
13 Andrea Pratichetti
12 Gideon La Grange
11 Tommaso Iannone
10 James Ambrosini
9 Fabio Semenzato
8 Manoa Vosawai
7 Valerio Bernabò
6 Dean Budd
5 Corniel Van Zyl (captain)
4 Marco Fuser
3 Jacobus Roux
2 Giovanni Maistri
1 Michele Rizzo
Replacements:
16 Franco Sbaraglini
17 Ignacio Fernandez-Rouyet
18 Pedro Di Santo
19 Enrico Ceccato
20 Filippo Giusti
21 Christian Loamanu
22 Luca Morisi
23 Brendan Williams
Head Coach: Franco Smith