But the Blues flyer stayed on the pitch and was the tormentor in chief with two tries as Wales secured the Six Nations title and in turn denied England a first Grand Slam in a decade.
With five games still to go in the RaboDirect PRO12 it now appears that Cuthbert will miss some if not all of their closing fixtures.
"Alex suffered a grade two hamstring strain in the first 30 minutes of the match against England. He is expected to be out for between four to six weeks," read a statement released by the Blues.
The 22-year-old's impressive Six Nations, in which he notched four tries, has made him a hot tip to go on this summer's British & Irish Lions Tour.
But if the injury is at the longer end of the scale in terms of recovery the youngster will be short of match practice before the squad's first game against the Barbarians in Hong Kong on June 1.