And former Glasgow Warrior Brown, who left the Scottish outfit for Saracens in 2010, believes he can form a winning partnership with the 22-year-old.
Harley is welcomed by interim Scotland coach Scott Johnson into the side that were defeated by England last Saturday, and although the Crewe-born forward was in the squad for last year's championship his only appearance for the national side came in June against Samoa.
But with a Murrayfield bow on the horizon for Harley, Brown insists he will be happy to pass on his experience.
Brown told The Scotsman: "If he wants it I'll speak to him and give him a bit of advice, but he strikes me as the sort of guy that takes anything thrown at him in his stride, and I'm sure it will be the same on Saturday.
"Though I moved away [to Saracens] I'm still a big fan of the two Scottish teams and I would say more so Glasgow, obviously, as an ex-player, so I've seen Rob play.
"He got a shot at six and has come in and done very, very well. It's been said that he's a very strong boy who works incredibly hard, and I'm just looking forward to playing alongside him."