They sit fifth in the RaboDirect PRO12 table, despite being one of the season's early pace-setters, winning their first five league games.
Fly-half Ruaridh Jackson said last week that the Christmas period could define their season and the man who plays inside him is hoping Edinburgh are short of their best on Boxing Day.
"Edinburgh have changed a lot so some of their players are not as familiar as they used to be," Cusiter told the Scotsman.
"If anything perhaps they are a little up and down and if they have a weakness it is probably their inconsistency. When they are on form they are very, very good
"We were frustrated and disappointed by our Heineken Cup results so are keen to get back to winning ways in the league. This game is huge for us."
Edinburgh have been one of the RaboDirect PRO12's most improved sides this season, under the stewardship of South African Alan Solomons.
And Cusiter believes it could be one of Solomons' countrymen, who followed him to Murrayfield this summer, that will offer a real threat on Thursday.
"I've been impressed by Cornell du Preez, he looks like one to watch," he added. "And Greig Laidlaw makes them tick, he's very smart.
"We had a couple of poor performances in the Heineken Cup. We were very consistent at the start of the season but we have to get back to the basics now."
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