The game will also see the debut as head coach of the white and green for Marius Goosen.
The back three consists of Brendan Williams, Luke McLean and Ludovico Nitoglia, with Christian Loamanu called to be paired with Alberto Sgarbi at centre.
Mat Berquist is paired with Edoardo Gori as the halfbacks.
The back row is Robert Barbieri at number eight, while Manoa Vosawai and Alessandro Zanni will be the flankers.
Captain Antonio Pavanello and Corniel Van Zyl are the locks, while in front there will be Lorenzo Cittadini, Leonardo Ghiraldini and Alberto De Marchi.
Starting line-up:
15 Brendan Williams
14 Ludovico Nitoglia
13 Christian Loamanu
12 Alberto Sgarbi
11 Luke McLean
10 Mat Berquist
9 Tobias Botes
8 Robert Barbieri
7 Alessandro Zanni
6 Manoa Vosawai
5 Corniel Van Zyl
4 Antonio Pavanello (captain)
3 Lorenzo Cittadini
2 Leonardo Ghiraldini
1 Alberto De Marchi
Replacements:
16 Franco Sbaraglini
17 Michele Rizzo
18 Ignacio Fernandez-Rouyet
19 Marco Fuser
20 Valerio Bernabò
21 Dean Budd
22 Tobias Botes
23 James Ambrosini
Head Coach: Marius Goosen.
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