But with the Warriors having lost their last two RaboDirect PRO12 fixtures at home Lam senses an opportunity to pounce on Sunday.
"Connacht has never won at Scotstoun and this is something we want to change," said head coach Lam.
"Playing Glasgow is a huge test for us. They are a very direct side with one of the best defensive structures in the entire league."
Connacht will be without Craig Clarke, Nathan Whitey, Sean Henry and Brett Wilkinson for the trip to Glasgow but Lam is confident his young charges can step up to the plate.
"It's obviously a big disappointment for us losing Craig (Clarke), (Nathan) Whitey, Sean (Henry) and Brett (Wilkinson) - four of the frontliners from our forward pack," he added.
"But we have full confidence in our squad and this is another opportunity for our younger forwards to step up, with a start this week.
"Having Robbie (Henshaw) back in the starting XV is a bonus, especially with Gavin (Duffy) unavailable this week.
"The versatility of our young backs allows Robbie to move to full-back and Craig (Ronaldson) to slip into inside centre with Eoin (Griffin) moving outside him."
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