Luke Marshall and Darren Cave maintain their partnership in midfield. Paddy Jackson has been released by Ireland and starts at outhalf, with Ruan Pienaar moving back to his more familiar position at scrumhalf.
Up front Callum Black starts at loosehead, with Tom Court named on the bench. Rob Herring continues at hooker with Ricky Lutton keeping his place at tighthead.
Johann Muller captains Ulster from the second row where he is joined by Iain Henderson, who has also been released from international duty.
Robbie Diack, Sean Doyle and Roger Wilson all start in an unchanged back row.
Twenty one year old centre, Stuart McCloskey, who is a member of the Hughes Insurance Ulster Academy, is named as a replacement and will make his first senior appearance for Ulster if called upon.
The game is sold out, the 11th match to be sold out at Ravenhill this season.
Ulster v Newport Gwent Dragons is live on BBC 2 Northern Ireland.
Ulster XV and replacements to face Newport Gwent Dragons, RaboDirect PRO12, Ravenhill, Friday 28th February (kick off 19:05) (15-9): J Payne, T Bowe, D Cave, L Marshall, R Scholes, P Jackson, R Pienaar; (1-8): C Black, R Herring, R Lutton, J Muller (Captain), I Henderson, R Diack, S Doyle, R Wilson; Replacements (16-23): N Annett, T Court, A Macklin, L Stevenson, M McComish, P Marshall, S McCloskey, D McIlwaine.