And perhaps no more so for Treviso and Zebre, who are battling for the Italian berth in next season's European Champions Rugby Cup.
At present, Zebre are in 11th spot and Treviso in 12th - both have 29 points but Zebre are 11th on points difference.
This weekend, Zebre travel to Glasgow Warriors while Treviso head to Newport Gwent Dragons, knowing they must better their countrymen's result.
Elsewhere, Edinburgh can move up one place to seventh, should they get the better of Leinster and Cardiff Blues slip up at the Scarlets, who have already sealed sixth place.
But Connacht will be hoping Leinster get the better of Edinburgh. Should that happen and Connacht win away to the Ospreys, Pat Lam's men would equal their best ever RaboDirect PRO12 finish of eighth.
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