Umberto Casellato has again made forced changes up front with the confirmation of Matteo Muccignat as tight-head prop, while experience will be the key factor in the second row with captain Antonio Pavanello and Corniel Van Zyl.
In the back row, together with confirmed Francesco Minto and Dean Budd, there will be Marco Barbini.
Half-backs revolutionized with Sam Christie at fly-half and Edoardo Gori with the number 9 jersey.
Among the backs, the back three is the same as last week against Edinburgh, but there is a brand new centre partnership of Enrico Bacchin and Michele Campagnaro.
On the bench, possible debuts for the two replacement props, Josè Novak and the Scottish D'arcy Rae, who recently arrived in Treviso.
Starting line-up:
15 Jayden Hayward
14 Simone Ragusi
13 Michele Campagnaro
12 Enrico Bacchin
11 Ludovico Nitoglia
10 Sam Christie
9 Edoardo Gori
8 Dean Budd
7 Francesco Minto
6 Marco Barbini
5 Corniel Van Zyl
4 Antonio Pavanello (captain)
3 Matteo Muccignat
2 Davide Giazzon
1 Matteo Zanusso
Replacements:
16 Albert Anae
17 Josè Novak
18 D'arcy Rae
19 Marco Fuser
20 Meyer Swanepoel
21 Simone Favaro
22 Alberto Lucchese
23 James Ambrosini
Head Coach: Umberto Casellato.
Guinness PRO12
Suite 208, Alexandra House,
The Sweepstakes
Ballsbridge, Dublin 4, Ireland