Denis Hurley is again named as captain while Donnacha Ryan is included in a matchday squad for the first time this season.
In total Foley makes just three changes to the starting line-up that defeated Glasgow Warriors at Irish Independent Park last weekend.
In the tight five, Dave Kilcoyne comes into the starting front row at loosehead alongside Eusebio Guinazu and BJ Botha, while Donncha O'Callaghan and Billy Holland form the second row partnership for the fourth successive game.
The back row sees Dave O'Callaghan return at 6 with Sean Dougall and CJ Stander continuing at 7 and 8 respectively.
There are no changes in the half backs and midfield with Duncan Williams, Ian Keatley, captain Denis Hurley and Keith Earls all retaining their starting positions.
With JJ Hanrahan remaining in situ at full-back, Felix Jones comes into the back three on the right wing alongside Ronan O'Mahony on the opposite flank.
Following the successful rehabilitation of a right foot injury sustained against Benetton Treviso in March of last year, the bench sees the welcome inclusion of Donnacha Ryan in a matchday 23 for the first time this season.
Munster: JJ Hanrahan; Felix Jones, Keith Earls, Denis Hurley - capt., Ronan O'Mahony; Ian Keatley, Duncan Williams; Dave Kilcoyne, Eusebio Guinazu, BJ Botha; Donncha O'Callaghan, Billy Holland, Dave O'Callaghan, Sean Dougall, CJ Stander.
Replacements: Kevin O'Byrne, John Ryan, Stephen Archer, Donnacha Ryan, Jack O'Donoghue, Neil Cronin, Andrew Smith, Andrew Conway.
Ospreys v Munster, Guinness PRO12 Round 17, Saturday March 7th at the Liberty Stadium - KO 2:40pm.
This game will be televised on Sky Sports while you can also follow the action on Twitter: @munsterrugby #OspVMun
Guinness PRO12
Suite 208, Alexandra House,
The Sweepstakes
Ballsbridge, Dublin 4, Ireland