Two changes in the front row see John Ryan and Stephen Archer come in to start on either side of Eusebio Guinazu, with Donncha O'Callaghan and Billy Holland remaining in situ in the second row.
The return of Tommy O'Donnell at openside is the only change to the back row with Dave O'Callaghan and CJ Stander continuing at 6 and 8 respectively.
Duncan Williams and Ian Keatley again team up in the half-backs, while Andrew Smith makes his first start since returning from injury, doing so outside captain Denis Hurley in the midfield.
The return of Smith sees Keith Earls move to the right wing with Simon Zebo returning to the opposite flank.
Felix Jones completes the back-three, reverting to full-back for this weekend's clash.
Having successfully rehabbed an ankle injury sustained during training in February, Duncan Casey is named amongst the replacements.
Munster: Felix Jones; Keith Earls, Andrew Smith, Denis Hurley - capt., Simon Zebo; Ian Keatley, Duncan Williams; John Ryan, Eusebio Guinazu, Stephen Archer; Donncha O'Callaghan, Billy Holland; Dave O'Callaghan, Tommy O'Donnell, CJ Stander.
Replacements: Duncan Casey, Dave Kilcoyne, BJ Botha, Paddy Butler, Jack O'Donoghue, Neil Cronin, JJ Hanrahan, Ronan O'Mahony.
Ticket Update
Over 17000 tickets have been sold Saturday's game and tickets will be available to purchase on the day.
Adult tickets start from €20 while Juniors can go from €7. Purchase tickets online from Ticketmaster.ie, from the Munster Rugby Ticket Offices in Thomond Park or Irish Independent Park, or by calling 0818 719 300.
Event Update
Both 6 Nations trophies will be presented at half-time in Thomond Park with Ireland Captain Paul O'Connell and Ireland Women's Captain Niamh Briggs in attendance.