Head coach Alan Solomons has made just one enforced change to the last week's starting XV.
Moving up from the bench to full back, in place of Jack Cuthbert who is carrying an injury from last weekend's win, is Tom Brown. Two of last week's try scorers, Dougie Fife and Tim Visser, retain their places on the wing along with the centre partnership of Sam Beard and Andries Strauss, at outside and inside centre respectively.
There's no change in the halfback pairing with Phil Burleigh at stand-off and Sam Hidalgo-Clyne, who racked up 25 points last Friday, at scrum half.
The pack is also unchanged since last weekend with Alasdair Dickinson at loosehead, W P Nel at tighthead and Ross Ford at hooker. Anton Bresler and Friday's man of the match Ben Toolis maintain their partnership at lock with Roddy Grant at openside and Stuart McInally at blindside.
Coming on to the bench to cover Tom Brown's move into the starting XV is full back/stand-off Carl Bezuidenhout and retaining his place in the substitutes is scrum half Nathan Fowles, recently announced as signing for the club on a one-year deal.
Head coach Alan Solomons said: "Last Friday was fantastic but it lies in the past and we are now moving forward on Zebre.
"Every game for us is vital and we need to perform accordingly."
Edinburgh Rugby team v Zebre, Friday 24 April, BT Murrayfield, k/o 7.35pm
15 Tom BROWN
14 Dougie FIFE
13 Sam BEARD
12 Andries STRAUSS
11 Tim VISSER
10 Phil BURLEIGH
9 Sam HIDALGO-CLYNE
1 Alasdair DICKINSON
2 Ross FORD
3 WP NEL
4 Anton BRESLER
5 Ben TOOLIS
6 Stuart McINALLY
7 Roddy GRANT
8 Mike COMAN (captain)
Substitutes
16 Neil COCHRANE
17 Rory SUTHERLAND
18 John ANDRESS
19 Fraser MCKENZIE
20 Cornell DU PREEZ
21 Nathan FOWLES
22 Tom HEATHCOTE
23 Carl BEZUIDENHOUT
Hugh Blake is with Glasgow Warriors until the end of the season
Damien Hoyland, Chris Dean and Jamie Farndale are currently with Scotland 7s
Injury update
Jack Cuthbert (groin), Allan Dell (ankle), David Denton (head), Grant Gilchrist (arm), Sean Kennedy (shoulder), Tomas Leonardi (head), Nick McLennan (groin), Matt Scott (shoulder), Greig Tonks (hamstring), Hamish Watson (hamstring)