Glasgow Warriors, Ospreys, Ulster and Munster will do battle later this month with a trophy on the line and this weekend is more than enough to whet the appetite.
With the venues of the two semi-finals yet to be decided, home advantage is at stake when league leaders Glasgow visit the Liberty Stadium and Ulster host Munster in an all-Irish affair.
Away from the play-offs the race for the top six is on, with Scarlets in pole position after securing a mammoth result at the Millennium Stadium on Judgement Day.
In front of more than 52,000 supporters, Wayne Pivac's men rounded off a box-office afternoon of rugby in the Welsh capital with a 29-10 victory over Newport Gwent Dragons.
Next up for them is an all-Welsh clash with Cardiff Blues at Parc y Scarlets, the visitors seeking to bounce back from Judgement Day defeat to the high-flying Ospreys.
Edinburgh lie just one point back in seventh and haven't had long to dwell on their agonising Challenge Cup final defeat to Gloucester.
The Scottish side fought valiantly at the Twickenham Stoop but ultimately a Ross Ford try and eight points from the boot of Sam Hidalgo-Clyne were just not enough to see a first ever European trophy head back to Scotland.
The Dragons are next up for Alan Solomons' men under the Friday night lights, while eighth-placed Connacht travel to Zebre knowing they need victory to stay in the hunt.
Zebre, however, have plenty to play for too, knowing that victory at the Stadio Sergio Lanfranchi could move them above Italian rivals Benetton Treviso.
With a Champions Cup place on offer the higher finisher of the two, only three points separate them with just two rounds to play.
However, Treviso will no doubt be determined to take it out of Zebre's hands, starting with their visit to Leinster on Friday.
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