The second change to the forwards sees hooker Eusebio Guinazu trading places with Duncan Casey this week, as the Argentinian international packs down with Dave Kilcoyne and Stephen Archer.
While the unchanged back row of Captain Peter O'Mahony, Tommy O'Donnell and CJ Stander complete the pack.
Denis Hurley is the only change to the backline as he joins Andrew Smith in the centre partnership with Simon Zebo, Keith Earls and Felix Jones continuing as the back three.
Finally with the half-back pairing of Conor Murray and Ian Keatley in place, the out-half will make his 99th appearance for the province on Saturday.
Munster: Felix Jones; Keith Earls, Andrew Smith, Denis Hurley, Simon Zebo; Ian Keatley, Conor Murray; Dave Kilcoyne, Eusebio Guinazu, Stephen Archer; Donnacha Ryan, Paul O'Connell; Peter O'Mahony Capt., Tommy O'Donnell, CJ Stander.
Replacements: Duncan Casey, John Ryan, BJ Botha, Billy Holland, Jack O'Donoghue, Duncan Williams, JJ Hanrahan, Ronan O'Mahony.