But this weekend they face a much sterner test when they travel to Leinster, and it's the first of four consecutive clashes against the Irish provinces.
After their visit to the RDS Arena, they face trips to Connacht, Munster and Ulster while BT Sport Cardiff Arms Park is transformed into an official fanzone for the Rugby World Cup.
Yet Blues head coach Wilson says he is ready for the challenge.
"We have spoken a lot about this period in the last few weeks; it is a great challenge to go to the likes of the RDS and some of these venues away from home," he said.
"The good thing is they are broken up with weeks off, but it is a heck of a challenge to play four games away from home to all the Irish provinces.
"However, if we come away with a few wins or do well in the games it will do us the world of good in terms of a confidence boost and points for the season."
Rhys Patchell and Josh Turnbull each scored hat-tricks for the Blues against Zebre last time out and Wilson is in high spirits.
He added: "We go this weekend full of confidence after a good home win, scoring 11 tries, but we also know that going to the RDS is a big challenge and a very different one, no disrespect, to the home game against Zebre."
Follow us on Facebook, join the conversation on Twitter, sign up to our YouTube channel for extensive match highlights and sign up for our newsletter for regular updates on the GUINNESS PRO12.
63x46.png){kind=logo}