An all new front row sees Dave Kilcoyne and Duncan Casey come back in with John Ryan making his first start of the season. Donnacha Ryan is another to make his first Munster start of the season and does so partnering Dave Foley in the second row.
Dave O'Callaghan returns at 6 with Jack O'Donoghue continuing at 7 and captain CJ Stander completes the back row in switching back to number 8 for tomorrow's encounter.
Conor Murray and Ian Keatley resume their partnership for the first time this season in the half-backs with Francis Saili and Keith Earls forming a new pairing in the midfield.
The only personnel change amongst the back-three sees winger Ronan O'Mahony make his first start of the current campaign. Gerhard van den Heever remains on the right wing and Simon Zebo makes the move to full-back.
Uruguayan international Mario Sagario is again in line to make his first appearance for the province after being named amongst the replacements.
On the injury front, Billy Holland (ankle) has completed his return to play rehabilitation and is expected to play a part in Cork Constitution's All Ireland League encounter against Young Munster at Tom Clifford Park while squad captain Peter O'Mahony's knee surgery is expected to take place in a fortnight.
Munster: Simon Zebo; Gerhard van den Heever, Keith Earls, Francis Saili, Ronan O'Mahony; Ian Keatley, Conor Murray; Dave Kilcoyne, Duncan Casey, John Ryan; Donnacha Ryan, Dave Foley; Dave O'Callaghan, Jack O'Donoghue, CJ Stander - capt.
Replacements: Niall Scannell, James Cronin, Mario Sagario, Robin Copeland, Jordan Coghlan, Tomás O'Leary, Rory Scannell, Denis Hurley.
Edinburgh v Munster, Guinness PRO12 Round 7, Saturday November 7th at Murrayfield - KO 5.15pm.
This game will be televised on Sky Sports. For Twitter updates follow @munsterrugby
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