This afternoon they face Wasps at the RDS and Jonathan Sexton will be making his first European start since returning home to the Irish province.
Leo Cullen's men have lost just one of the four pool games in which they have clashed with Wasps, but the English side have won their last two European encounters on the road.
And it is likely a few Ulster fans will be tuning into see what All Blacks back Charles Piutau, who will be playing at the Kingspan Stadium next season, can do.
Sunday November 15, kick-off 1pm UK/IRE
Leinster: Ian Madigan, Zane Kirchner, Fergus McFadden, Noel Reid, Dave Kearney, Johnny Sexton, Eoin Reddan; Jack McGrath, Richardt Strauss, Mike RosS, Devin Toner, Mike McCarthy, Jordi Murphy, Sean O'Brien, Jamie Heaslip.
Replacements: Sean Cronin, Cian Healy, Tadhg Furlong, Hayden Triggs, Jack Conan, Luke McGrath, Cathal Marsh, Garry Ringrose.
Wasps: Charles Piutau, Christian Wade, Elliot Daly, Ben Jacobs, Frank Halai, Ruaridh Jackson, Joe Simpson, Matt Mullan, Carlo Festuccia, Jake Cooper-Woolley, Joe Launchbury, Bradley Davies, Sam Jones, George Smith, Nathan Hughes
Replacements: Ashley Johnson, Simon McIntyre, Phil Swainston, James Gaskell, Guy Thompson, Dan Robson, Alex Lozowski, Sailosi Tagicakibau
Ospreys are one of the GUINNESS PRO12 teams to have suffered the most through the absence of their stars due to the Rugby World Cup but a hefty victory over Zebre last weekend sets them in good stead to take on Exeter Chiefs.
Dan Biggar pulls the strings at fly-half while Alun Wyn Jones, Justin Tipuric and Dan Lydiate are just some of the big names in the pack as Ospreys meet Exeter for the first time in European competition.
And they will be looking to help their side overcome an English hoodoo, with the Ospreys winless in their last nine matches against Premiership opposition in the competition.
Exeter are off to a flying start in the Premiership - currently in second place - but history suggests this encounter could be a tight one, as their last five games in the competition have been settled by seven points or fewer.
Sunday November 15, kick off 17:30 UK/IRE
Ospreys: Dan Evans, Dafydd Howells, Jonathan Spratt, Josh Matavesi, Eli Walker, Dan Biggar, Brendon Leonard, Paul James, Scott Baldwin, Dmitri Arhip, Lloyd Ashley, Alun Wyn Jones, Dan Lydiate, Justin Tipuric, James King
Replacements: Sam Parry, Ryan Bevington, Aaron Jarvis, Rory Thornton, Dan Baker, Tom Habberfield, Sam Davies, Ben John
Exeter Chiefs: Jack Nowell, Matt Jess, Henry Slade, Sam Hill, James Short, Gareth Steenson, Wil Chudley, Alec Helpburn, Luke Cowan-Dickie, Tomas Francis, Mitch Lees, Damian Welch, Dave Ewers, Don Armand, Julian Salvi.
Replacements: Jack Yeandle, Carl Rimmer, Moray Low, Ollie Atkins, Tom Johnson, Dave Lewis, Ian Whitten, Michele Campagnaro
Newport Gwent Dragons head coach Kingsley Jones will welcome his old side, Sale Sharks, to Rodney Parade, as the Welsh region look to improve on their recent impressive European Rugby Challenge Cup record.
The Dragons have won seven of their last nine matches in the competition and Europe could be just what they need after suffering a tight defeat to Ulster last time out in the GUINNESS PRO12.
They will have to cope without Wales No.8 Taulupe Faletau, who failed a late fitness test, though Nick Crosswell has returned from a three-week suspension to take his place on the bench.
Sale Sharks have made 13 changes to their starting XV following a narrow defeat to Harlequins and will look to keep up their fine record against Welsh teams in the competition - having won eight of their last nine encounters.
Sunday November 15, kick-off 15:15 UK/IRE
Newport Gwent Dragons: Carl Meyer, Ashton Hewitt, Adam Hughes, Adam Warren, Nick Scott, Dorian Jones, Sarel Pretorius, Boris Stankovich, Elliot Dee, Shaun Knight, Cory Hill, Rynard Landman, Lewis Evans, Ollie Griffiths, Ed Jackson
Replacements: Rhys Buckley, Phil Price, Brok Harris, Matthew Screech, Nick Crosswell, Charlie Davies, Jason Tovey Ross Wardle
Sale Sharks: Tim Jeffers, Tom Brady, Mark Jennings, Sam Bedlow, Charlie Ingall, Nick MacLeod, James Mitchcell, James Flynn, Neil Briggs, Brian Mujati, Jon Mills, Andrei Ostrikov, Magnus Lund, Andrew Hughes, Vili Fihaki
Replacements: Cameron Neild, Jake Pope, Ross Harrison, George Nott, Josh Beaumont, Joe Ford, John O'Donnell, Neville Edwards
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