And Humphreys admitted that defeat had hit his troops hard but could only look on and smile as they put things right on Saturday with a 26-9 win over Connacht.
Man of the match Eli Walker, Justin Tipuric, Jonathan Thomas and Kahn Fotuali'i all crossed for Ospreys leaving Humphreys to reflect on a job well done.
"I don't think people really understand how much it took out of the boys last week, in terms of the disappointment of it," he said.
"So it was great to see the group stay together and get what we wanted out of the game.
"It's probably one of the most difficult weeks to juggle.
"You build up for a peak and it doesn't quite work out for you but the effort is phenomenal, it can be difficult to pick yourself straight back up again, particularly when you are up against a team where the public perception is they get beaten a lot, you're at home, and people maybe expect it to be easier for you than the reality of it.
"We know Connacht are a dangerous side, it was a really tough game, and although not perfect, the endeavour and the effort from the group was outstanding.
"It took us a little while to get over the disappointment of last week, but the endeavour was outstanding. We got what we wanted out of the game but there's room for improvement."