Munster v Stade Francais
Munster are reeling from three Champions Cup defeats in a row but Anthony Foley has named a side capable of wrestling the team's pride back.
CJ Stander captains a team including Ireland internationals Ian Keatley, Conor Murray, Simon Zebo and Tommy O'Donnell, as they bid to stop French champions Stade Francais from winning at Thomond Park for the first time.
The Irish province have won both of their last home game against Stade Francais - 2000 and 2004 - who will be captained by Italy skipper Sergio Parisse on Saturday.
Stade Francais are four points behind Pool 4 leaders Leicester Tigers, but they have not won two away games in the group stages since 2004/05.
Saturday, 1pm, Thomond Park
Munster: 15 Simon Zebo, 14 Keith Earls, 13 Francis Saili, 12 Rory Scannell, 11 Ronan O'Mahony, 10 Ian Keatley, 9 Conor Murray, 1 Dave Kilcoyne, 2 Mike Sherry, 3 Mario Sagario, 4 Dave Foley, 5 Mark Chisholm, 6 Billy Holland, 7 Tommy O'Donnell, 8 CJ Stander
Replacements: 16 Kevin O'Byrne, 17 Liam O'Connor, 18 John Ryan, 19 Donnacha Ryan, 20 Robin Copeland, 21 Jack O'Donoghue, 22 Tomas O'Leary, 23 Lucas Amorisino
Stade Francais: 15 Hugo Bonneval, 14 Waisea Nayacalevu, 13 Jonathan Danty, 12 Paul Williams, 11 Julien Arias, 10 Morne Steyn, 9 Julien Dupuy, 1 Zak Taulafo, 2 Laurent Panis, 3 Rabah Slimani, 4 Paul Gabrillagues, 5 Pascal Pape, 6 Sekou Macalou, 7 Jonathan Ross, 8 Sergio Parisse
Replacements: 16 Zurabi Zhvania, 17 Heinke van der Merwe, 18 Paul Alo Emile, 19 Hugh Pyle, 20 Sylvain Nicolas, 21 Julien Tomas, 22 Jules Plisson 23, Jeremy Sinzelle
Saracens v Ulster
Saracens' unbeaten start to the season finally came to an end last weekend as they lost to Harlequins at the Stoop.
But they remain perfect in the Champions Cup and head into this fixture knowing they beat Ulster 27-7 at the Kingspan Stadium earlier in the competition.
However, Les Kiss' Ulster are on a high after backing up their back-to-back victories over Toulouse with a dramatic comeback against Oyonnax in France - at one stage being 23-0 down.
Ireland wing Andrew Trimble is an important returnee for the Ulstermen, and though a loss at Allianz Park will not kill their knockout chances, with 13 points so far any positive result would be welcome.
Saturday, 3:15pm, Allianz Park
Saracens: 15 Ben Ransom, 14 Chris Ashton, 13 Marcelo Bosch, 12 Brad Barritt, 11 Chris Wyles, 10 Owen Farrell, 9 Richard Wigglesworth, 1 Mako Vunipola, 2 Jamie George, 3 Petrus du Plessis, 4 Maro Itoje, 5 George Kruis, 6 Michael Rhodes, 7 Will Fraser, 8 Billy Vunipola
Replacements: 16 Schalk Brits, 17 Richard Barrington, 18 Juan Figallo, 19 Jim Hamilton, 20 Jackson Wray, 21 Neil de Kock, 22 Charlie Hodgson, 23 Duncan Taylor
Ulster: 15 Jared Payne, 14 Andrew Trimble, 13 Luke Marshall, 12 Stuart McCloskey, 11 Craig Gilroy, 10 Paddy Jackson, 9 Ruan Pienaar, 1 Kyle McCall, 2 Rory Best, 3 Wiehan Herbst, 4 Alan O'Connor, 5 Franco van der Merwe, 6 Robbie Diack, 7 Sean Reidy, 8 Roger Wilson
Replacements: 16 Rob Herring, 17 Callum Black, 18 Ricky Lutton, 19 Lewis Stevenson, 20 Clive Ross, 21 Paul Marshall, 22 Ian Humphreys, 23 Rory Scholes
Leinster v Bath
Leinster are the early losers from Pool 5 - the so-called 'group of death' - but they are not taking the final two rounds half-heartedly by the look of their team.
Captain Jamie Heaslip misses the clash due to a head injury but there are starts for the likes of Zane Kirchner, Isa Nacewa, Dave Kearner and Rhys Ruddock.
But there is also a blend of youth with that experience - six players make their first European starts and in that bunch, Peter Dooley and Ross Molony appear for the first time in the competition.
As for Bath, a gutsy loss to Toulon last week has their qualification hopes hanging by a thread, and name an unchanged side.
Saturday, 5:30pm, RDS Arena
Leinster: 15 Zane Kirchner, 14 Isa Nacewa, 13 Garry Ringrose, 12 Ben Te'o, 11 Dave Kearney, 10 Ian Madigan, 9 Luke McGrath, 1 Peter Dooley, 2 James Tracy, 3 Tadhg Furlong, 4 Ross Molony, 5 Miek McCarthy, 6 Rhys Ruddock, 7 Josh van der Flier, 8 Jordi Murphy
Replacements: 16 Sean Cronin, 17 Jack McGrath, 18 Marty Moore, 19 Tom Denton, 20 Sean O'Brien, 21 Eoin Reddan, 22 Jonathan Sexton, 23 Noel Reid
Bath: 15 Anthony Watson, Semesa Rokoduguni, 13 Jonathan Joseph, 12 Kyle Eastmond, 11 Matt Banahan, 10 George Ford, 9 Chris Cook, 1 Max Lahiff, 2 Rob Webber, 3 David Wilson, 4 Stuart Hooper, 5 Dom Day, 6 Matt Garvey, 7 Francois Louw, 8 Leroy Houston
Replacements: 16 Ross Batty, 17 Nick Auterac, 18 Henry Thomas, 19 Charlie Ewels, 20 David Denton, 21 Jonathan Evans, 22 Rhys Priestland, 23 Tom Homer
Leicester Tigers v Benetton Treviso
Manu Tuilagi will be the name on everyone's lips at Welfroad as the Leicester Tigers and England centre makes his first start for 15 months following injury.
Niki Goneva is another big name to come in at wing, though Freddie Burns replaces Owen Williams at fly-half after the latter suffered a fractured jaw in Tigers' dramatic victory over fierce rivals Northampton Saints last week.
Leicester are sitting on four wins in four in Pool 4 while Treviso are yet to pick up a point in a difficult European campaign.
The Italians' only away victory in the competition to date is their success at Newport Gwent Dragons in 2007.
Saturday, 7:45pm, Welford Road
Leicester: 15 Tommy Bell, 14 Adam Thompstone, 13 Mathew Tait, 12 Manu Tuilagi, 11 Vereniki Goneva, 10 Freddie Burns, 9 Ben Youngs, 1 Logovii Mulipola, 2 Tom Youngs, 3 Dan Cole, 4 Dom Barrow, 5 Graham Kitchener, 6 Michael Fitzgerald, 7 Tom Croft, 8 Jordan Crane
Replacements: 16 Harry Thacker, 17 Marcos Ayerza, 18 Fraser Balmain, 19 Sebastian De Chaves, 20 Laurence Pearce, 21 Jono Kitto, 22 Seremaia Bai, 23 Peter Betham
Treviso: 15 Jayden Hayward, 14 Andrea Pratichetti, 13 Sam Christie, 12 Alberto Sgarbi, 11 Simone Ragusi, 10 James Ambrosini, 9 Alberto Lucchese, 1 Alberto de Marchi, 2 Omel Gega, 3 Salesi Manu, 4 Filo Paulo, 5 Jean_Francois Montauriol, 6 Marco Lazzaroni, 7 Francesco Minto, 8 Robert Barbieri
Replacements: 16 Davide Giazzon, 17 Cherif Traore, 18 Filippo Filippetto, 19 Marco Fuser, 20 Alessandro Zanni, 21 Abraham Jurgens Steyn, 22 Enrico Bacchin, 23 Luke McLean
CHALLENGE CUP
Worcester Warriors v Zebre
It has been a season of progress for Zebre in Europe, and if they win on Saturday, it will be the first time they have picked up three Challenge Cup victories in a single season.
Zebre have already beaten Worcester Warriors at the Stadio Sergio Lanfranchi, and need the same kind of performance at Sixways to keep in contention for the knockouts.
They are on eight points, nine behind runaway leaders Gloucester in Pool 4, but have only won once away from home in five attempts.
But Worcester, who have plumped to give some of their younger players experience for the contest, had not lost to Italian opposition in 12 games prior to this season - records are made to be broken.
Saturday, 3pm, Sixways
Worcester: 15 Ben Howard, 14 Andy Short, 13 Alex Grove, 12 Andy Symons, 11 Dean Hammond, 10 Tiff Eden, 9 Luke Baldwin, 1 Ryan Bower, 2 Ben Sowrey, 3 Gareth Milasinovich, 4 Dan Sanderson, 5 Darren O'Shea, 6 Huw Taylor, 7 Carl Kirwan, 8 Marco Mama
Replacements: 16 Daniel George, 17 Mike Daniels, 18 Nick Schonerty, 19 Tevita Cavubati, 20 Matt Cox, 21 Charlie Mulchrone, 22 Ryan Mills, 23 Perry Humphreys
Zebre: 15 Ulrich Beyers, 14 Dion Berryman, 13 Giulio Bisegni, 12 Matteo Pratichetti, 11 Kayle van Zyl, 10 Kelly Haimona, 9 Guglielmo Palazzani, 1 Andrea de Marchi, 2 Tommaso D'Apice, 3 Dario Chistolini, 4 Valerio Bernabo, 5 Marco Bortolami, 6 Jacopo Sarto, 7 Johan Meyer, 8 Dries van Schalkwyk
Replacements: 16 Oliviero Fabiani, 17 Bruno Postiglioni, 18 Pietro Ceccarelli, 19 Federico Ruzza, 20 Jean Cook, 21 Luke Burgess, 22 Giulio Toniolatti, 23 Edoardo Padovani
Brive v Connacht
Connacht may have lost to Newcastle Falcons last time out but they are still in control of Pool 1, two clear on 13 points.
Pat Lam has made ten changes to the team that suffered a last-gasp loss to Scarlets in the GUINNESS PRO12, with USA fly-half AJ MacGinty handed his third start of the season.
The history books are in Connacht's favour, as Brive have not won back-to-back Challenge Cup games for almost two years.
And Lam's troops are currently on a seven-game winning record against French opposition.
Saturday, 7:45pm, Stade Amedee-Domenech
Brive: 15 Romain Sola, 14 Guillaume Namy, 13 Thomas Laranjeira, 12 Christopher Tuatara, 11 Benito Masilevu, 10 Matthieu Ugalde, 9 Jean-Baptisete Pejoine, 1 Goderzi Shvelidze, 2 Thomas Acquier, 3 Kevin Buys, 4 Victor Lebas, 5 Arnaud Mela, 6 William Whetton, 7 Fabien Sanconnie, 8 Sisa Koyamaibole
Replacements: 16 Guillaume Ribes, 17 Damien Lavergne, 18 Yusuf Tuncer, 19 Wilhelm Steenkamp, 20 Poutasi Luafutu, 21 Teddy Iribaren, 22 Nicolas Bezy, 23 Arnaud Mignardi
Connacht: 15 Tiernan O'Halloran, 14 Danie Poolman, 13 Rory Parata, 12 Bundee Aki, 11 Matt Healy, 10 AJ MacGinty, 9 Ian Porter, 1 Ronan Loughney, 2 Jason Harris Wright, 3 Rodney Ah You, 4 Ultan Dillane, 5 Aly Muldowney, 6 Sean O'Brien, 7 James Connolly, 8 John Muldoon
Replacements: 16 Tom McCartney, 17 Denis Buckley, 18 Finlay Bealham, 19 George Naoupu, 20 Eoghan Masterson, 21 Caolin Blade, 22 Jack Carty, 23 Peter Robb
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