Those changes occur up front with Stephen Archer getting in on this ocasion ahead of BJ Botha while Dave O'Callaghan gets the nod over Paddy Butler at number 6.
Penney announced the side this morning after training in a sun kissed UL where the squad spent 90 minutes being put through their paces by Penney, Simon Mannix and Anthony Foley.
Munster: Denis Hurley; Doug Howlett capt, Casey Laulala, James Downey, Luke O'Dea; Ian Keatley, Duncan Williams; Wian du Preez, Damien Varley, Stephen Archer; Donncha O'Callaghan, Billy Holland; Dave O'Callaghan, Sean Dougall, James Coughlan.
Replacements: Mike Sherry, Dave Kilcoyne, BJ Botha, Dave Foley, Paddy Butler, Peter Stringer, Scott Deasy, Ivan Dineen
Guinness PRO12
Suite 208, Alexandra House,
The Sweepstakes
Ballsbridge, Dublin 4, Ireland