Jonathan Sexton - who has now scored 228 points in 18 Leinster appearances so far this season - links up with Eoin Reddan at half-back with Luke Fitzgerald, Shane Horgan and Isa Nacewa again named in the back three.
In the pack, Heinke van der Merwe will make his 31stappearance of the season and is one of two forward changes as Shane Jennings comes in to link up with Sean O'Brien and Jamie Heaslip in the back-row.
Leo Cullen skippers the team and starts alongside Scotland's Nathan Hines, while the province can call upon three Ireland internationals off the bench in Cian Healy, Kevin McLaughlin and Devin Toner.
LEINSTER:
15: Isa Nacewa
14: Shane Horgan
13: Brian O'Driscoll
12: Fergus McFadden
11: Luke Fitzgerald
10: Jonathan Sexton
9: Eoin Reddan
1: Heinke van der Merwe
2: Richardt Strauss
3: Mike Ross
4: Leo Cullen CAPTAIN
5: Nathan Hines
6: Sean O'Brien
7: Shane Jennings
8: Jamie Heaslip
REPLACEMENTS:
16: Aaron Dundon
17: Cian Healy
18: Stan Wright
19: Devin Toner
20: Kevin McLaughlin
21: Paul O'Donohoe
22: Ian Madigan
23: Eoin O'Malley
REFEREE: Nigel Owens (WRU)