In a largely unchanged side from the landmark victory against their local rivals, Pat Leach replaces centre Ashley Smith who is to be rested and Dan Way comes in for Ben Castle.
"Ashley could have made it this weekend," said Dragons Head Coach Darren Edwards "but he has worked really hard all season and we wanted to look after him to make sure he's ready for next season. We also wanted to take to opportunity to further expose Dan Way to Magners League rugby."
Newport Gwent Dragons
Steffan Jones, Adam Hughes, Tom Riley, Pat Leach, Aled Brew, Jason Tovey, Wayne Evans; Phil Price, Lloyd Burns, Dan Way, Luke Charteris, Adam Jones, Danny Lydiate, Gavin Thomas, Toby Faletau.
Replacements
Tom Willis, Hugh Gustafson, Ben Castle, Andrew Coombs, Joe Bearman, Matthew Watkins, Jon Evans, Mathew Jones.
Referee: Alan Lewis
Assistant Referees: Tim Hayes, Sean Bricknell