Alessandro Zanni and Robert Barbieri are in the back row with prop Ignacio Fernandez Rouyet and Valerio Bernabo at lock.
Gonzalo Garcia is in the centre, while half backs Fabio Semenzato and Kristopher Burton also return.
Paul Derbyshire and Luke McLean will be on the bench.
Corniel Van Zyl iremains in the second row this weekend, while Joe Maddock will again wear the number 15 shirt after his positive performace against Leinster.
Benetton Treviso team:
15 Joseph Maddock
14 Ludovico Nitoglia
13 Andrea Pratichetti
12 Gonzalo Garcia
11 Michele Sepe
10 Kristopher Burton
9 Fabio Semenzato
8 Robert Barbieri
7 Alessandro Zanni
6 Benjamin Vermaak
5 Corniel Van Zyl
4 Valerio Bernabò
3 Ignacio Fernandez Rouyet
2 Leonardo Ghiraldini (captain)
1 Michele Rizzo
Replacements:
16 Diego Vidal
17 Matteo Muccignat
18 Lorenzo Cittadini
19 Gonzalo Padrò
20 Paul Derbyshire
21 Simon Picone
22 Tobias Botes
23 Luke McLean
Head Coach: Franco Smith.