Brett Wilkinson will start in the loosehead prop position while new signing Nathan White gets his first start tomorrow as tighthead prop.
Elsewhere in the backs, Dave McSharry has been promoted to a starting berth, replacing Mata Fifita in the centre.
Scarlets are riding high after two successive wins and are perched proudly on top of the league table.
Eric Elwood was very pleased with his team's performance in Parma last week and the 30-17 win over Zebre but knows there is a lot of work to do this weekend.
"We played well in Zebre scoring three tries away from home and securing our first win of the season. The lads showed huge character in Italy, especially when we were forced into making so many changes in the second half. Tomorrow poses another challenge as Scarlets are top of the league and are playing very well. They've had a great start to the season, scoring 10 tries in the process. We will really have to step it up against this Scarlets side but the lads are well up for the challenge."
15. Gavin Duffy (Captain)
14. Tiernan O'Halloran
13. Eoin Griffin
12. Dave McSharry
11. Fetu'u Vainikolo
10. Miah Nikora
9. Kieran Marmion
1. Brett Wilkinson
2. Ethienne Reynecke
3. Nathan White
4. Michael Swift
5. Mike McCarthy
6. Andrew Browne
7. Willie Faloon
8. Eoin McKeon
Replacements from:
16. Adrian Flavin
17. Dennis Buckley
18. Rodney Ah You
19. David Gannon
20. Johnny O'Connor
21. Dave Moore
22. Matthew Jarvis
23. Robbie Henshaw