Kevin McLaughlin featured for 80 minutes on Saturday for the first time since last May and he was joined by the returning Eoin O'Malley who had missed the province's recent victories over ASM Clermont Auvergne and Ulster.
A number of the Ireland representatives who were unavailable for the last two fixtures as part of the IRFU player welfare programme - including Gordon D'Arcy, Cian Healy, Jamie Heaslip and Jonathan Sexton - are in contention alongside the likes of Leinster Academy graduates David Kearney (2 tries), Fergus McFadden and Niall Morris who were all try-scorers in the bonus point victory over Connacht at the weekend.
Leinster lie in third place in the Magners League table, a point ahead of the Ospreys.
Friday's game marks Leinster's 50th competitive fixture in the RDS and looks set to be played in front of another strong crowd. Ticket sales are approaching the 15,000 mark and are on sale now from www.leinsterrugby.ie, Spar (Donnybrook), the Leinster Rugby Store (Donnybrook), Champion Sports (Grafton Street) as well as Ticketmaster outlets nationwide.