Its a curiosity that the Dragons seem to mark the stages of historical records for Benetton as Enrico Pavanello achieved the same milestone last season against the same team.
The man affectionately known as 'Dingo', will be celebrated with a solo exit, accompanied by Chanel, his five year old daughter.
For him, there will also be a special shirt to commemorate the day, and as usual a new pair of boots for the occasion.
Many international players return after Italian duty at the World Cup in New Zealand.
Alberto Sgarbi and Lorenzo Cittadini have already played against Ulster, but there are some new faces to be added, like lock Corniel Van Zyl and flanker Alessandro Zanni.
In the backs, Fabio Semenzato takes back his position as scrum half, while Tommaso Benvenuti will play on the wing.
Robert Barbieri, Paul Derbyshire and Luke McLean will sit on the bench ready to go in.
In the pack, Michele Rizzo and Enrico Ceccato are in the front row, with captain Antonio Pavanello as lock and Marco Filippucci and Francesco Minto in the back row.
Kristopher Burton remains in the control room after his strong start to the season and the starting lineup is completed by Ezio Galon as outside centre and Ludovico Nitoglia at fullback.
Tobias Botes is on the bench, and also Pedro Di Santo will be back in action, after suffering groin problems that have kept him off the field in for the games against Scarlets and Ulster.
John Lacey will officiate, he has also been appointed for the first match of the Heineken Cup against Saracens and he was in charge of the game against the Ospreys last year in Treviso.
It will be the fifth game between the two teams.
Starting lineup:
15 Ludovico Nitoglia
14 Tommaso Benvenuti
13 Ezio Galon
12 Alberto Sgarbi
11 Brendan Williams
10 Kristopher Burton
9 Fabio Semenzato
8 Marco Filippucci
7 Alessandro Zanni
6 Francesco Minto
5 Corniel Van Zyl
4 Antonio Pavanello (captain)
3 Lorenzo Cittadini
2 Enrico Ceccato
1 Michele Rizzo
On the bench:
16 Diego Vidal
17 Matteo Muccignat
18 Pedro Di Santo
19 Valerio Bernabò
20 Robert Barbieri
21 Paul Derbyshire
22 Tobias Botes
23 Luke McLean
Head Coach: Franco Smith