The Dragons won the most recent match between the two teams, 28-15 at Rodney Parade on 29 April, to end an eight game losing run against the Blues.
Newport Gwent Dragons Squad
Martyn Thomas, Tonderai Chavhanga, Adam Hughes, Lewis Robling, Aled Brew, Jason Tovey; Wayne Evans; Nathan Williams, Lloyd Burns, Nathan Buck, Adam Jones, Rob Sidoli, Danny Lydiate, Gavin Thomas, Toby Faletau.
Replacements:
Steve Jones, Phil Price, Dan Way, Jevon Groves, Darren Waters, Joe Bedford, Anitelea Tuilagi, Will Harries.
Guinness PRO12
Suite 208, Alexandra House,
The Sweepstakes
Ballsbridge, Dublin 4, Ireland