Scotland cap Rory Lamont, who had a successful first game back from injury for the Warriors back-up team against the Reivers on Monday (final score 34-12 in the Warriors favour) starts at fullback, meaning Sean Marsden drops out of the side.
Lineen said: "Winning our home games is so importance to us in the Magners League and we'll be looking to build upon our last win here against Munster. At the moment, we're one place ahead of the Reivers in the League table so I can't emphasise enough how much of a must win game this is for both sides."
Lamont added: "I've been working very hard on my speed and weights to make sure I'm ready for coming back. Monday's game was tough going but I needed it. I hadn't done much contact work in a while so was really keen to get back into things."
On the bench, there is also one change - Sam Pinder returns as replacement scrum half meaning Ben Addison drops out of the side as Dan Parks and Scott Barrow remain as the replacement backs.
GLASGOW WARRIORS TEAM v BORDER REIVERS
15 Rory Lamont
14 Hefin O'Hare
13 Graeme Morrison
12 Andrew Henderson
11 Thom Evans
10 Colin Gregor
9 Graeme Beveridge
1 Justin Va'a
2 Fergus Thomson*
3 Euan Murray*
4 Andy Newman
5 Alastair Kellock* CAPTAIN
6 Andrew Wilson*
8 John Beattie*
7 John Barclay*
SUBSTITUTES
16 Scott Lawson*
17 Kevin Tkachuk
18 Dan Turner
19 Donnie Macfadyen
20 Sam Pinder
21 Dan Parks
22 Scott Barrow
Unavailable for selection due to injury: James Eddie (ankle), Colin Shaw (ankle).
The following National Academy players are being made available to play for their clubs this weekend:
*Member of the Scottish Institute of Sport. **Member of the West of Scotland Institute of Sport