In the pack, Allister Hogg switches from blind to openside flanker for Alasdair Strokosch as Matt Mustchin fills the berth left by Hogg at No 6.
The Gunners go into the game on the back of four straight defeats and Blackadder knows the side has to move on. He said: "We're all disappointed with the results - that's an understatement. As a coach I'm hurting but tomorrow is about getting back on track.
"We haven't been up to the mark and tomorrow is a huge challenge. We have to show ourselves and show our supporters that we have moved on. I was really impressed with the attitude against Munster but silly mistakes let us down," he added.
The Glasgow Warriors announced today that they have signed the Gunners' Argentinean international wing/fullback Francisco Leonelli for two years. On Leonelli, who joined Edinburgh last summer, Blackadder said: "Francisco has had a good year with us and we wish him all the best with Glasgow."
Edinburgh Gunners:15 Hugo Southwell; 14 Chris Paterson CAPTAIN, 13 Marcus Di Rollo, 12 Peter Jorgensen, 11 Simon Webster; 10 Phil Godman, 9 Mike Blair; 1 Alasdair Dickinson, 2 Andrew Kelly, 3 Craig Smith; 4 Alastair Kellock' 5 Scott Murray; 6 Matt Mustchin, 8 Simon Taylor, 7 Allister Hogg
Substitutes:16 Dave Hewett, 17 Allan Jacobsen, 18 Dave Duley, 19 Alasdair Strokosch, 20 Rory Lawson, 21 Matt Dey, 22 Francisco Leonelli