Ireland duo Trevor Hogan and Keith Gleeson return to the starting line-up for the penultimate game of the season and Gleeson's inclusion will mark his final home appearance for the province.
There is a familiar look to the remainder of the forwards, with Ollie le Roux starting alongside Bank of Ireland Player of the Year Bernard Jackman and Stan Wright.
Shane Horgan has recovered from illness to take his place in a strong backline which includes fellow Ireland internationals Girvan Dempsey, Rob Kearney and captain Brian O'Driscoll.
Chris Whitaker partners Jonathan Sexton at-half back with Felipe Contepomi partnering O'Driscoll at centre.
An end of season player and supporter reception, in association with Magners, will take place post-match for all Leinster season ticket holders in Shelbourne Hall 2 inside the RDS.
Saturday's game will comfortably exceed the 14,000 average that has helped make Leinster the 'Best Supported Team' in the Magners League for the second successive season.
Tickets are still on sale from Spar (Donnybrook) as well as from the Leinster Rugby Store (Donnybrook) and there will also be several hundred available from Ticketmaster outlets around the ground on Saturday afternoon.
LEINSTER:
15: Girvan Dempsey
14: Shane Horgan
13: Brian O'Driscoll CAPTAIN
12: Felipe Contepomi
11: Rob Kearney
10: Jonathan Sexton
9: Chris Whitaker
1: Ollie le Roux
2: Bernard Jackman
3: Stan Wright
4: Trevor Hogan
5: Malcolm O'Kelly
6: Shane Jennings
7: Keith Gleeson
8: Jamie Heaslip
REPLACEMENTS:
16: Brian Blaney
17: Stephen Knoop
18: Cameron Jowitt
19: Stephen Keogh
20: Chris Keane
21: Christian Warner
22: Luke Fitzgerald
Guinness PRO12
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